Spontaneous Reporting Systems: Benefits and Pitfalls when Interpreting Safety Data of Non-Steroidal Anti-Inflammatory Drugs.- Drug Utilization Studies: A Useful Tool for the Safety Evaluation of Non-Steroidal Anti-Inflammatory Drugs?.- Post-Marketing Surveillance as an Instrument of Adverse Drug Reaction Monitoring.- Non-Steroidal Anti-Inflammatory Drugs: Epidemiological Studies of Adverse Reactions.- The SPALA Project - An Intensive Monitoring System for Non-Steroidal Anti-Inflammatory Drugs.- Toxicity Analysis of Mild Analgesics in Clinical Use.- Gastrointestinal Tract Toxicity - A Risk Factor for Non-Steroidal Anti-Inflammatory Therapy.- Incidence of Mild and Severe Skin Reactions Associated with the Use of Non-Steroidal Anti-Inflammatory Drugs.- Kidney Function Impairment: Do Relevant Differences between Non-Steroidal Anti-Inflammatory Drugs Exist?.