This issue of PET Clinics focuses on Evolving Role of PET-guided Interventional Oncology Based Procedures, and is edited by Drs. Abass Alavi (the Consulting Editor of PET Clinics), Marnix Lam, Stephen Hunt, and Ghassan El-Haddad. Articles will include: Y-90 PET/CT and radioembolization; FDG-PET and radioembolization; Ga-68-PSMA PET and HCC; C11 Acetate-PET for hepatocellular carcinoma patients undergoing radioembolization; FDG-PET for Ablation Treatment Planning, Intraprocedural Monitoring and Response; Global FDG Response Assessment to IR Procedures with Concomitant Immunotherapy; PET Assessment of Abscopal Effects and Pseudoprogression from IR Procedures; FDG-PET for monitoring response to embolotherapy (TACE) in primary and metastatic liver disease; and more!