Mouse Genetics: Methods and Protocolsprovide selected mouse genetic techniques and their application in modeling varieties of human diseases. The chapters are mainly focused on the generation of different transgenic mice to accomplishthe manipulation of genes of interest, tracing cell lineages and modeling human diseases. Composed in the highly successfulMethods in Molecular Biologyseries format, each chapter contains a brief introduction, a list of necessary materials, systematic, readily reproducible methods and a notes section, which shares tips on troubleshooting in order to avoid known pitfalls.
Comprehensive and authoritative,Mouse Genetics: Methods and Protocolspromises to deliver fundamental techniques and protocols to geneticists, molecular biologists, cell and developmental biologists, students and postdoctoral fellows working in the various disciplines of mouse biology and modeling human disease.
