Potato (Solanum tuberosum L.) is grown in over 100 countries throughout the world. As a staple food, potato is the fourth most important crop after rice, wheat, and maize, and has historically contributed to food and nutrition security in the world. Global interest in potato increased recently as world food prices soared, threatening the global food security and stability. Unlike major cereals, potato is not a globally traded commodity, and prices are usually determined by local production costs. Thus, potato is increasingly regarded as a vital food-security crop and as a substitute for costly cereal imports. With such importance, the 29 chapters in the edited book address the issues of sustainable potato production. This book begins with an introduction on sustainable potato production and global food security, and then presents eight case studies selected globally and covering different issues relevant to sustainable potato production in both developed and developing countries.