The 2020-21 Guide To Medications For The Therapy Of Diabetes Mellitus

Newly updated to reflect the latest research and medical guidance, the 2020-21 Guide to Medications for the Treatment of Diabetes offers a bridge between drug handbooks and pharmacology texts.Focusing entirely on diabetes drugs, this reference is divided into two sections: - Drugs used to manage hyperglycemia, and - Management of diabetic comorbidities.The first section includes: - Pharmacologic Therapy for Type 1 Diabetes - Management of Hyperglycemia in Type 1 DM- info from practical use of insulin, pathophysiology, treatment strategy - Insulins: RAIAs, Short-acting insulins, intermediate-acting insulins, LAIAs, Concentrated Insulins, Insulin pumps and patches, inhaled insulins, mixed and mixing insulin, use in Type 1, use in Type 2 - Pharmacologic Therapy for Type 2 Diabetes - Management of Hyperglycemia in Type 2- brief overview, pathophysiology, treatment strategy, overview of medications - Biguanides - TZDs - SUs - Glinides - SGLT-2 Inhibitors - AGIs - DPP-IV inhibitors - GLP Ras - Amylin mimetics - BARs - DA-2 agonistsEach chapter in Section 1 includes:

- Drug class overview and role in diabetes treatment - Pharmacology: a. Mechanism of action, b. Pharmacokinetics - Treatment Advantages/Disadvantages: General for the class, b. When applicable, a discussion of evidence that supports the benefits of using a particular drug in a class over another in the same class (eg, Avandia vs Actos) - Therapeutic Considerations: a. Significant Warnings/Precautions, b. Special Populations, c. Pharmacogenomics, d. Adverse effects and monitoring, e. Drug Interactions, f. Dosage and administration - Table with Doses and Dose Adjustments - List of important combination products - References

The second section includes: - Cardiovascular Disease and Risk Management - Microvascular Complications and Foot Care - Medications for the Management of Hypertension - Medications for the Management of Hyperlipidemia - Antiplatelet Therapy - Medications for Smoking Cessation - Medications for the Management of Neuropathy (peripheral and autonomic) - Medications for the Management of Nephropathy - Medications for the Management of Retinopathy - Medications for the Management of Depression - Medications for the Management of Hypoglycemia - Medications for the Management of Obesity - Immunizations in Patients with DiabetesEach chapter in Section 2 includes:

- An overview of the condition or problem - Goals of treatment - Overview of the medications and rationale for the medications used for the problem - Overview of each class of medication - Overview of combination therapy: a. first combination, b. second combination - Doses and Dose Adjustments for the more salient medications - List of important combination products - References