Excerpt from The American Journal of the Medical Sciences, Vol. 104
In a recent communication (1892) Brieger, Kitasato, and Wasser mann1 have published the results of their interesting experiments with a bouillon made from the thymus gland of the calf. It was found that the tetanus bacillus cultivated in this bouillon did not form spores, and had comparatively little virulence. Mice or rabbits inoculated with it in small doses to for a mouse - proved to be subsequently immune. And the blood-serum of an immune rabbit injected into the peritoneal cavity of a mouse to c.c. - was found to give it im munity from the pathogenic action of a virulent culture of the tetanus bacillus. Similar results were obtained with several other pathogenic bacteria cultivated in the thymus bouillon - spirillum of cholera, bacillus of diphtheria, typhoid bacillus.
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