Excerpt from Wesselsbron Disease: A Literature Review
Wesselsbron disease, an infectious, noncontagious, arthropod-borne viral disease, occurs naturally in sheep and man. The disease causes abortions in pregnant ewes, deaths in newborn lambs, and manifests itself as a febrile influenzalike syndrome in man. Mosquitoes serve as the natural vector for the disease transmission.
The disease present on the African continent was initially isolated in the Union of South Africa in 1955. The clinical manifestations, pathology, and epizootiology closely resemble those of Rift Valley fever. The virus is suspected of causing abortions in cattle. Experimentally, cattle, horses, domestic swine, subhuman primates, mice, rabbits and guinea pigs have been infected. Fever, anorexia, and depression are seen pregnant ewes and deaths in lambs. In man, fever and myalgia are the symptoms reported. Liver degeneration is the most common pathological finding. ‘mouse inoculation is utilized for confirmatory diagnosis. An attenuated virus vaccine has been developed for prophylaxis in cattle and sheep.
This publication presents a literature review of major references on Wesselsbron disease.
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